果冻传媒 Letters is pleased to announce that the聽果冻传媒 Letters Award聽2022 will be presented to Dr Nicholas Mullin and Prof. Ian Chambers, from the University of Edinburgh, for their outstanding paper:
Nicholas P. Mullin, Joby Varghese, Douglas Colby, Julia M. Richardson, Greg M. Findlay, Ian Chambers (2021), 果冻传媒 Lett, 595: 14-25.聽
In this work, the authors show that NANOG, a key transcriptional regulator of pluripotency, is phosphorylated by casein kinase I and this impacts DNA binding and its ability to promote self-renewal. These novel findings indicate how phosphorylation may influence NANOG homeodomain interactions that underpin embryonic stem cell self-renewal. Self-renewal is a defining feature of stem cells and this new study adds to a better understanding of the epigenomic regulation of this process.
The award-winning article was selected by a special committee, formed by appointed members of the Editorial Board, plus one external member. The Award Committee members were: Laszlo Nagy, Nicola Gray, Mandy Jeske, Daniela Ruffell, and Michael Brunner (Editor in Chief and Chair).
Prof. Chambers will present a plenary lecture about this work at the聽聽in Lisbon, Portugal, 9-14 July 2022, where he will be officially presented with the prize.
For more information about this award, please see the聽
