果冻传媒

This is intended for researchers with experience in protein engineering who have begun exploring computational tools and now wish to move beyond the basics. The focus will be on applying these tools to solve concrete problems through hands-on assignments, practical exercises, and supporting theoretical lectures.

Participants will learn the principles and rationale behind modern design strategies to address challenges such as engineering protein鈥損rotein interactions, large assemblies and molecular machines, small-molecule binders, enzymes, and membrane proteins. Building on the thematic workshops, participants will spend at least two full days working in small teams on a personalized protein design project, applying generative and computational methods to real research questions. The program emphasizes active collaboration among the trainees and interactions between the trainees and the lecturers/tutors, through the group assignment, discussions, and opportunities for poster presentations.

The course is also supported by the RosettaCommons and will take place in the pleasant coastal town of Blankenberge, in Belgium.

Organizers: Anastassia Vorobieva, Noelia Ferruz, Alena Khmelinskaia, Ajasja Ljubeti膷

The 果冻传媒 Advanced Lecture Course 鈥楾umour Microenvironment: From tumour heterogeneity to therapy resistance鈥� will bring together an international and interdisciplinary community of basic, translational and clinical researchers to discuss key aspects and new conceptual advancements in the field of tumour microenvironment, mechanisms of therapy resistance, cancer cell heterogeneity and cell plasticity.

The course aims to provide a comprehensive overview of the physiological functions of the distinct cell types that comprise the tumour microenvironment and how these cells are implicated in disease progression and therapy resistance. Topics that will be covered include tumour vascular biology, tumour adaptive and innate immunity, cancer metastasis, and cancer cell plasticity. New technologies and tools to study the tumour microenvironment, such as tissue biomechanics, gene therapy for immune cell reprogramming and single-cell technologies will be highlighted. The course will also showcase the clinical relevance of targeting the tumour microenvironment and will demonstrate how findings from basic research in model organisms can lead to improved therapeutic applications.

The scientific programme of the course includes seven thematic sessions and is designed to offer advanced training and in-depth discussions. Talks will be delivered by internationally recognised experts in the field, alongside selected presentations from young scientists, promoting active participation and scientific exchange across career stages. Young scientists will also have the opportunity to present and discuss their work during poster sessions and structured networking activities.

In addition to the scientific content, the course will place strong emphasis on training, networking, and career development. Dedicated workshops will focus on career paths in academia and industry, how to improve scientific writing & funding applications, and 鈥榤eet the expert鈥� session, where young researchers will have the opportunity to meet in small groups with senior scientists who are leaders in their field and discuss specific issues. There will also be plenty of opportunities throughout the meeting for participants and speakers to informally interact in a relaxed and idyllic atmosphere, during the social events, and by spending free time at the beach.

Overall, the course will provide a stimulating and supportive environment for learning, discussion, and collaboration, and will contribute to the advancement of the tumour microenvironment research field.

Organizers: Ioanna Keklikoglou, Kairbaan Hodivala-Dilke, Antoni Celia-Terrassa, Damya Laoui, Panayotis Verginis

Without biological membranes, life wouldn鈥檛 exist, hence biomembranes can easily be considered as the most essential structures of living cells. These membranes, containing both lipids and proteins isolate cells and their internal organelles from their surroundings and are complex structures that vary considerably in composition depending on their functions and location. A full understanding of the structural and compositional complexity of these membranes, their biogenesis, their interactions and their function will require multi-disciplinary approaches. To obtain detailed insights into the pathways and mechanisms leading to the assembly and proper functioning of membranes, co-operative research efforts of biochemists, biophysicists, structural biologists, and molecular and cell biologists are required.

The provides an excellent platform and opportunity to acquire an integrated overview of the structure, function and biogenesis of biological membranes in the context of the biogenesis of organelles and their components. It will also provide promising students in the field a chance to get personally acquainted with leaders of the various disciplines, to acquire insight into the possibilities offered by different experimental approaches and to discuss and learn about the multiple techniques in membrane-related research. In addition to scholarly scientific lectures, the program also contains as an essential element various mentoring sessions on work-life balance, career planning, and responsible conduct of science. Moreover, the program will allow for a total of 20 young scientist participants to give oral presentations of their work.

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Organizers: Eefjan Breukink, Alison Forrester, F. Ulrich Hartl

The is a one-week advanced course taking place in Spetes, Greece, aimed at junior researchers that work in structural biology. At this course, students will learn to understand, use, and interpret data from a multitude of different techniques including cryo-electron microscopy, nuclear magnetic resonance spectroscopy, X-ray crystallography, cryo-electron tomography, small-angle X-ray scattering, mass spectrometry, and single-molecule methods such as optical tweezers and F枚rster resonance energy transfer. Students will learn to integrate data from these different methods via advanced computational and machine learning approaches. In doing so, students will learn to go beyond static molecular structures, to create 3D models that reveal dynamic interactions and behaviours that are crucial for understanding biology and biomedical research. Integration also brings into light entire new classes of biomolecules鈥攊n particular, those that are dynamic and difficult to study as well as complexes of ever-increasing sizes.

The course will include plenary lectures by esteemed scientists: Alexandre Bonvin, Ann Terry, Arwen Pearson, Birthe B. Kragelund, Bj枚rn Forsberg, Frauke Gr盲ter, Gregers Rom Andersen, Jay Groves, Lindsay Baker, Martin Pacesa, Martin Weik, Mikael Akke, Nikos Hatzakis, P茅tur O Heidarsson and Rasmus Kock Flygaard. There will also be poster sessions, panel discussions, journal club, group discussions, and a mentoring session led by Professor聽Emeritus聽Jane Clarke. In addition to the scientific activities, there will be networking events, social dinners and an excursion around the island.

The deadline for application submissions is 31 January 2026 and the number of places available is strictly limited to 44. There are 8 果冻传媒 Youth Travel Fund Grants available to help cover registration fees and travel expenses.

Additional information on the course can be obtained from this聽 from the course organizers.

Organizers: Birthe Kragelund, Gregers Rom Andersen, Kresten Lindorff-Larsen, Rasmus Kock Flygaard

The 8^th will be held in Erice, Sicily (Italy) on 13鈥�19 May 2026. The course aims to provide a broad coverage of state-of-the-art research on ion channel and transporter physiology, function and structure. The topics covered by the course span multiple scales, from approaches in electrophysiology, cryo-electron microscopy, and molecular simulations to probe their structure-function relationship at the single molecule level, to methods to investigate the roles of these proteins in complex physiological systems and how their dysfunction leads to disease.

The course features world-renowned experts from diverse backgrounds, from academia to industry and publishing. Speakers will elucidate the role of channels and transporters in human disease and the use of animal models to investigate the underlying mechanisms. Furthermore, the relevance to the research for the clinic and industry/innovation will also be highlighted. This breadth of scope will ensure the course has a broad appeal and constitutes a timely forum to discuss cutting-edge research.

YTF Grant application deadline: 1 March聽2026

Additional information on the course can be obtained from this 聽by the course organizer.

Organizers: Anna Moroni, Stephan Pless, Alessio Accardi

Deadline for applications: 15 April 2026

The 果冻传媒 Advanced Lecture Course on Human fungal pathogens (HFP) has established itself as a reference event in the field, with ten successful editions since 2005. The upcoming 2026 meeting marks the 11th edition of this renowned course, bringing together international experts and early-career researchers to explore key advances in fungal pathogenesis.

The will focus on the molecular, biochemical, and genetic mechanisms underlying fungal virulence, host-pathogen interactions, antifungal resistance, and immune evasion. The programme includes keynote lectures, plenary talks, interdisciplinary workshops, and short oral presentations selected from participant abstracts.

The course will cover a wide range of cutting-edge topics鈥攆rom fungal genomics and RNA biology to cross-kingdom microbial interactions and immune dynamics鈥攐ffering a comprehensive view of fungal infections at the molecular level.

The primary aim of HFP2026 is to share cutting-edge knowledge with early-career scientists and create valuable networking opportunities with leaders in fungal biology. Through its fully residential and interactive format, the course offers an immersive environment for learning, discussion, and career development.

Image credit: S. Delli猫re and Institut Pasteur/CNRMA.

Additional information on the course can be obtained from this聽聽by the course organizer.

Organizers: Jessica Quintin, Clarissa Nobile, Agostinho Carvalho

The 果冻传媒 Advanced Lecture Course ‘Transglutaminases in biological processes’ will bring together an international and interdisciplinary community of researchers to explore current advances in transglutaminase biology and their relevance to health and disease. The course (which follows the 果冻传媒 Workshop ‘Transglutaminases in human disease processes’ in 2024) aims to provide a comprehensive overview of the physiological functions of transglutaminase enzymes, including their roles in signal transduction, protein crosslinking, and extracellular matrix organisation, as well as their contribution to a broad spectrum of pathological conditions. Topics covered will include cardiovascular and neurological diseases, cancer, inflammation and autoimmunity, fibrosis and tissue remodelling, metabolic disorders, and emerging disease contexts, together with new experimental approaches and tools to study and modulate transglutaminase activity.

The scientific programme is designed to offer advanced training and in-depth discussion, combining plenary and keynote lectures with seven thematic sessions led by internationally recognised experts. Each session will include invited talks alongside selected presentations from early-career researchers, promoting active participation and scientific exchange across career stages. Young scientists will also be involved in moderating discussions and presenting their work through short talks and poster flash presentations.

In addition to the scientific content, the course will place strong emphasis on training, networking, and career development. Dedicated sessions will address career paths in academia and industry, effective scientific communication, and funding opportunities, while ample time will be reserved for informal interactions and social activities. Overall, the course will provide a stimulating and supportive environment for learning, discussion, and collaboration, and will contribute to the continued development of the transglutaminase research community.

Organizers: Luigi Leanza, Elisabetta Verderio Edwards, Nicoletta Bianchi, Jeffrey Keillor, Jambrovics K谩roly

The ability of cells to perceive and correctly respond to their environment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in the interplay, dynamics or localization of the involved molecules are responsible for many diseases such as cancer, autoimmunity and diabetes. By increasing the understanding of the complex interplay between these various components and their dynamics over time the related diseases can be treated more effectively. Because of the recent technological revolution in advanced light microscopy (i.e. functional imaging of molecules, development of caged compounds and biosensors) it is now possible to directly monitor the dynamics of these (single) molecules and numerous biosensors in living cells.聽 Microscopic techniques like Super-resolution Microscopy, FLIM-FRET, FRAP and FCS allow us to visualize cellular signaling complexes and their dynamics in time and will be the topic of this 果冻传媒 practical course.

This 6-day advanced microscopy course for up to 20 experienced graduate students, postdocs and scientists will integrate theoretical lectures with hands-on experiments and practical experience. National and international experts in the field of microscopy will give an overview of 鈥渟tate-of-the-art鈥� imaging techniques and applications in biological research.

Organizers: Mark Hink