The will be held in 12鈥�18 October 2026 on the island Spetses, Greece. Brain function depends on the exquisitely controlled spatial and temporal release of neurotransmitters, which are stored in synaptic vesicles (SVs). In addition, synaptic function relies on profound cargo and lipid flux and on organizational principles to recycle and enrich distinct sets of proteins/lipids in local functional and dynamic environments. Recent advances in techniques such as high-resolution imaging, in vitro reconstitution, electrophysiology, molecular modelling, and biophysics have provided remarkably detailed and unsurpassed insights into the molecular components and mechanisms, structural architecture, signaling pathways and pathogenesis underlying neurotransmitter release.
This course aims to provide an integrated perspective on synaptic vesicle dynamics, bringing together experts at the forefront of closely related and highly relevant topics including membrane trafficking, lipid dynamics, neuronal exocytosis, and the organization of supramolecular structures and molecular condensates. The talks will emphasize molecular mechanisms, structure-function relationships, molecular causes of neurological disease, and state-of-the-art technologies. In an informal setting, poster sessions, oral presentations, and casual meet-the-expert rounds will stimulate interactions between students, postdocs and lecturers, establishing scientific and personal networks.
Organizers: Thomas S枚llner, Bernd Helms, Felix Wieland
